A Novel Neuronal Therapeutic Approach for Cardiac Arrhythmias

Abstract

Cardiac arrhythmias, one of the leading cardiovascular diseases in young adults, has been found to lack specific therapies. Previous therapies have revolved around radiofrequency ablation, anti-arrhythmic medication, and defibrillators, which have majorly been unsuccessful in being specific and come with a variety of side effects. However, the autonomic nervous system has a significant role to play in triggering and perpetuating arrhythmias and has ample scope of targeting the agents responsible for the modulation of the cardiac wave. This review tries to include evidence of therapies that could emerge from targeting the neuronal markers and pathways in the autonomic system for arrhythmias.