Spontaneous coronary artery dissection (SCAD) and fibromuscular dysplasia (FMD) are rapidly evolving in terms of their medical and scientific research. Since our publication titled Spontaneous Coronary Artery Dissection and Fibromuscular Dysplasia: Vasculopathies With a Predilection for Women  was first published online in July 2020, there has been increasing interest in SCAD and FMD, particularly focused on the genetics of these conditions. SCAD has historically been underdiagnosed and only in recent years widely acknowledged and diagnosed by specialist cardiologists. It is now being increasingly recognized by general medical physicians as exemplified by the recent review article in The New England Journal of Medicine . This is important, given its systemic vascular associations and the need for all physicians to recognize these and manage accordingly.