Cardiac Problems and Concentration of Ambient Nitrogen Dioxide

*Szyszkowicz M
Department Of Cardiovascular Surgery, Health Canada, Canada

*Corresponding Author:
Szyszkowicz M
Department Of Cardiovascular Surgery, Health Canada, Canada

Published on: 2019-07-23


Background: Environmental epidemiology studies report an association of cardiac health conditions with concentration of ambient air pollutants. As high level of air pollution increases the health risk.
Aim: To estimate the association in the form of the parametric concentration-response shapes.
Methods: A case-crossover technique is applied to realize the statistical models. The concentration of air pollution is transformed and submitted into the model. The parameters of the concentration-response function are estimated to satisfy the goodness of fit criterion. Emergency department (ED) visits for cardiac health problems are used as health outcomes. Nitrogen dioxide is used as ambient air pollution exposure.
Results: Positive statistically significant associations were obtained between the numbers of ED visits and the concentration of nitrogen dioxide lagged by 0, 1, 2, and 3 days. Odds ratios are growing with increased concentration levels and are between 1.03 and 1.10.
Conclusion: A concentration-response function allows summarizing the associations between cardiac problems and ambient nitrogen dioxide.


Air pollution; Cardiac condition; Case-crossover; Concentration; Nitrogen dioxide


In this work, a new approach is described to represent the associations between the exposure to ambient air pollution and health conditions. Air pollution health effects are usually analyzed as a longterm or short-term exposure study. Here, we consider short-term exposure to ambient nitrogen dioxide (NO2). Cardiac related health problems are used as health outcomes. In this presentation, we estimate the association between daily concentration of nitrogen dioxide and these health conditions.

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