Heat can be transferred through nano-sealed particles by suspending them into a base fluid. Many experimental data have shown that nanofluids have much more thermal conductivity than conventional fluid. The main objective is to evaluate the role of copper oxide nanofluid in a channel that is compact and used for the application of heat. The evaluation of heat transfer performance has been calculated and the heat transfer rate of the compact channel goes above with an increase in the concentration of a base fluid of nanoparticles. At the same condition, if there is a nanofluid whose temperature is less at some factor, then the heat transfer rate is approximately 24% increases than base fluid.