Incidents of viral epidemics have escalated at an alarming rate during the previous decades. The most recent human coronavirus identified as COVID-19 (SARSCoV- 2) has already spread over the world. These epidemics constrain healthcare systems about employing standard medicines and diagnostic technologies. In this context, the application of nanotechnology provides new prospects for the development of novel techniques in terms of diagnosis, prevention, diagnosis and treatment of COVID-19. This review discusses nanotechnology-based strategies for diagnosis, prevention, and treatment of COVID-19, including nanomaterials for surface sterilization, face masks, personal protective equipment, disinfectants, nanocarrier systems and diagnostic systems for treatments and vaccine development. It presents a viewpoint on how nanotechnology may be utilized to battle against COVID-19.