Gold Nanoparticles as Nanocarriers in Cancer Targeted Therapy View PDF

^*Lopez AP
Department Of Genetics, Molecular Biology Laboratory, Universidad De Buenos Aires, Argentina

^*Corresponding Author:

Lopez AP
Department Of Genetics, Molecular Biology Laboratory, Universidad De Buenos Aires, Argentina
Email:aplopez@prensamedica.com.ar

Published on: 2021-12-30

Abstract

Functionalized gold nanoparticles are being used extensively for many biomedical applications and research has shown an abundant use in targeted delivery. AuNPs are small gold particles that have a diameter between 1nm to 100nm. More lately, these unique optoelectronic properties have been researched and employed in high technology applications like organic photovoltaics, sensory probes, therapeutic agents, drug delivery in biological and medical applications, electronic conductors and catalysis. The optical and electronic properties of gold nanoparticles are tunable by altering the size, shape, surface chemistry, or aggregation state. This review will provide a comprehensive review of recent advances and future perspectives of AuNp’s in targeted therapy and diagnostics.

Keywords

Gold Nanoparticles, Nanoparticles, Nanocarriers, Targeted Therapy

Introduction

Cancer is one of the leading causes of death in history in current society. The cause of a disease can be lifestyle, genetics and it varies from person to person. There are many treatments in the diagnosis of cancer to either ease the pain of the patient or to reduce the tumor altogether. Chemotherapy, Radiation therapy, Immunotherapy, targeted therapies are currently in use to treat cancer. Targeted therapy has found prominence in current medicine due to applications to activate the required size of the tumor. This has provided a wide application in treatment. Metals like Zinc, Silver, Gold, and Titanium are widely considered as carriers for the same in which gold nanoparticles have shown prominent results.

AuNps are being used extensively in biological, biotechnology, diagnostics and mainly in targeted therapy. Their unique properties are providing versatile applications to carry antibodies, proteins and can provide multiple applications in biomedical applications. The use of gold in medicine has been seen in history and it has shown some prominent results [1]. The reason for extensive use also is due to its ease in synthesizing, being economical and reliable. They can be easily modified to any shape by changing conditions. And due to highly reactive surfaces, they can bind the molecules, drugs and make them valuable carriers.