Neurocardiology: Synergy between the Brain and the Heart View PDF

*Ariel Pablo Lopez
Department Of Genetics, Molecular Biology Laboratory, Universidad De Buenos Aires, Argentina

*Corresponding Author:
Ariel Pablo Lopez
Department Of Genetics, Molecular Biology Laboratory, Universidad De Buenos Aires, Argentina
Email:aplopez@prensamedica.com.ar

Published on: 2020-03-21

Abstract

The fundamental reciprocal processes are easily understood, the relationship within the brain and heart becomes ever more significant. The practice of connection linking brain and heart distinguished as Neurocardiology. Neurocardiology points to physiological reciprocation among nervous systems and cardiovascular.

Keywords

Neurocardiology; Atrial fibrillation; Heart; Brain; Cognitive disorders

Introduction

The fundamental reciprocal processes are easily understood, the relationship within the brain and heart becomes ever more significant. The practice of connection linking brain and heart distinguished as neurocardiology [1]. Neurocardiology points to physiological reciprocation among nervous systems and cardiovascular [2]. Baroreceptor reflex sensitivity further fluctuation in heart frequency rate are crucial parameters in reading the autonomic nervous system's impact on heart moreover brain movement [3,4]. A developing therapy from the past years about the brain-heart involvement with important possible outcomes for cardiovascular disorder care. Cerebrovascular injuries, transient ischaemic attacks are often triggered due to cardiac arrhythmias may be congestive heart failure [5,6].

Atrial fibrillation may lead to cognitive disorders that precede the incidence of TIAs or CVAs [7-9]. Atrial fibrillation is a hazard circumstance for cognitive dysfunction and hippocampal atrophy, particularly in the lack of apparent stroke. Hence, in assessing experimental therapies for atrial fibrillation, attention and tests of intrinsic brain probity should be respect. Another side, cerebrovascular dysfunction likely lead to disruptions in the electrocardiography and cardiac rhythm. Subarachnoid fracturing may get drastic variations in the electrocardiography and despite ventricular fibrillation, likely adequate prolongation of the QT-interval [10]. Anxiety problems and psychological stress are the syndromes of Takotsubo that can lead to ventricular tachycardia resulting in temporary left ventricular abnormality [11,12]. Stenting operation has major impacts on neurocognitive functioning [13]. The research remains unclear about the effect of intra-operational emboli and cognitive decline subsequent operation [14]. Alternatively a fixed number of intraoperational emboli, extra emphasis might place on unique structure, size, and place. Understanding of neurocognitive loss in cases with chronic vascular and congenital heart illness continues to challenge investigators and researchers alike [15]. For older patients with heart disease, exercise interventions may delay or slow down the cognitive decline. The remedial effects of the strong bonding within the nervous system, the brain, and the heart would begin to be gradually a central subject of future research [16]. The upcoming healing strategies in neurocardiology extends in several innovative therapies and the application of experimental integrative therapeutic concepts which bring toward account simultaneous constant degenerative including vascular complications as well as various drug moreover non-drug therapy intercommunications. Vagal invigoration, exercise education, electrical neurostimulation, music treatment, including new renal denervation are now useful solutions in the diagnosis of angina pectoris, heart problems and hypertension [17-19]. A different collection of patients can thrive until the correct interrelationship processes within the nervous system, brain and heart are illustrated [20]. Through a clearer idea of certain interactions, many effective clinical steps can be taken to support people of cardiovascular and cerebrovascular complications. Various pathogenetic pathways are related to brain infarction and heart disease. Coronary artery illness is normal in cases with transient ischemic attacks, frequently asymptomatic [21,22]. Maximum cases feeling transient ischemic attacks will ultimately mortal of myocardial infarction. Serious asymptomatic stenosis of the carotid artery is a stabler indicator of deadly myocardial infarction more than ipsilateral stroke [23,24]. Obviously, a proactive therapeutic strategy to carotid artery indicative and asymptomatic atherosclerosis should also be balanced by considering life-limiting coronary artery disease.

Treatment

The latest different experiments have shown that catheter-based thrombectomy is an efficient therapy for cases appropriately preferred. Interventional cardiology with its extensive unstoppable amenities during severe myocardial infarction will provide neuro-interventional facilities to load the prevailing holes in the coverage of community requirements. Clinical treatment of both heart and brain diseases didn't find in isolation. Cardiac conditions also impact neurological cases' moreover, neurological concerns are important in many cases of heart disorder. The neurologist should look at the heart for sure, and the cardiologist needs to take into account the mental effects of heart disease.

References

  1. Samuels MA (2007) The brain-heart connection. Circulation 116: 77-84.https://doi.org/10.1161/CIRCULATIONAHA.106.678995
  2. Van Buchem MA, Biessels GJ, Brunner la Rocca HP, de Craen AJ, et al. (2014) The heart-brain connection: a multidisciplinary approach targeting a missing link in the pathophysiology of vascular cognitive impairment. J Alzheimers Dis 42:S443-S451.https://doi.org/10.3233/JAD-141542
  3. La Rovere MT, Pinna GD, Raczak G (2008) Baroreflex sensitivity: measurement and clinical implications. Ann Noninvasive Electrocardiol 13:191-207.https://doi.org/10.1111/j.1542-474X.2008.00219.x
  4. La Rovere MT, Specchia G, Mortara A, Schwartz PJ (1988) Baroreflex sensitivity, clinical correlates, and cardiovascular mortality among patients with a first myocardial infarction. A prospective study. Circulation 78:816-824.https://doi.org/10.1161/01.CIR.78.4.816
  5. Freedman B, Potpara TS, Lip GY (2016) Stroke prevention in atrial fibrillation. Lancet 388:806-817.https://doi.org/10.1016/S0140-6736(16)31257-0
  6. Hyers TM, Agnelli G, Hull RD, Morris TA, Samama M, et al. (2001) Antithrombotic therapy for venous thromboembolic disease. Chest 119: 176S-193S.https://doi.org/10.1378/chest.119.1_suppl.176s
  7. Stroke Prevention in Atrial Fibrillation Investigators (1991) Stroke prevention in atrial fibrillation study: final results. Circulation 84:527-539.https://doi.org/10.1161/01.cir.84.2.527
  8. Hart RG, Halperin JL, Pearce LA, Anderson DC, Kronmal RA, et al. (2003) Lessons from the stroke prevention in atrial fibrillation trials. Ann Int Med 138:831-838.https://doi.org/10.7326/0003-4819-138-10-200305200-00011
  9. Smit MD, Van Gelder IC (2011) Risk-benefit ratio assessment for stroke prevention in intermediate risk atrial fibrillation patients: will TEE-based aspirin treatment fill the gap?. Nether Heart J 19:212-213.https://doi.org/10.1007/s12471-011-0119-z
  10. Van Gijn J, Rinkel GJ (2001) Subarachnoid haemorrhage: diagnosis, causes and management. Brain 124:249-278.https://doi.org/10.1093/brain/124.2.249
  11. Durrer D, Schoo L, Schuilenburg RM, Wellens HJ (1967) The role of premature beats in the initiation and the termination of supraventricular tachycardia in the Wolff-Parkinson-White syndrome. Circulation 36: 644-662.https://doi.org/10.1161/01.CIR.36.5.644
  12. Davis AM, Natelson BH (1993) Brain-heart interactions. The neurocardiology of arrhythmia and sudden cardiac death. Tex Heart Inst J 20:158-169.
  13. Gao L, Taha R, Gauvin D, Othmen LB, Wang Y, et al. (2005) Postoperative cognitive dysfunction after cardiac surgery. Chest 128:3664-3670.https://doi.org/10.1378/chest.128.5.3664
  14. Kahonen-Vare M, Brunni-Hakala S, Lindroos M, Pitkala K, StrandbergT, et al. (2004) Left ventricular hypertrophy and blood pressure as predictors of cognitive decline in old age. Aging Clin Exp Res 16:147-152.https://doi.org/10.1007/BF03324544
  15. Rimmer JH, Heller T, Wang E, Valerio I (2004) Improvements in physical fitness in adults with down syndrome. Am J Ment Retard 109: 165-174.https://doi.org/10.1352/0895-8017(2004)109<165:IIPFIA>2.0.CO;2
  16. Fonarow GC (2005) An approach to heart failure and diabetes mellitus. Am J Cardiol 96:47-52.https://doi.org/10.1016/j.amjcard.2005.06.005
  17. Vagus Nerve Stimulation Study Group (1995) A randomized controlled trial of chronic vagus nerve stimulation for treatment of medically intractable seizures. Neurol 45: 224-230.
  18. Belardinelli R, Georgiou D, Cianci G, Purcaro A (1999) Randomized,controlled trial of long-term moderate exercise training in chronic heart failure: effects on functional capacity, quality of life, and clinical outcome. Circulation 99:1173-1182.https://doi.org/10.1161/01.CIR.99.9.1173
  19. Jessurun GA, DeJongste MJ, Hautvast RW, Tio RA, Brouwer J, et al. (1999) Clinical follow?up after cessation of chronic electrical neuromodulation in patients withsevere coronary artery disease: a prospective randomized controlled study on putative involvement of sympathetic activity. Pacing Clin Electrophysiol 22:1432-1439.https://doi.org/10.1111/j.1540-8159.1999.tb00346.x
  20. Kozora E, Thompson LL, West SG, Kotzin BL (1996) Analysis of cognitive and psychological deficits in systemic lupus erythematosus patients without overt central nervous system disease. Arthri Rheumat 39:2035-2045.https://doi.org/10.1002/art.1780391213
  21. Millikan CH, McDowell FH (1978) Treatment of transient ischemic attacks. Stroke 9:299-308.https://doi.org/10.1161/01.str.9.4.299
  22. Palomeras Soler E, Casado Ruiz V (2010) Epidemiology and risk factors of cerebral ischemia and ischemic heart diseases: similarities and differences. Curr Cardiol Rev 6:138-149.https://doi.org/10.2174/157340310791658785
  23. Lal BK, Hobson II RW, Goldstein J, Geohagan M, Chakhtoura E, et al. (2003) In-stent recurrent stenosis after carotid artery stenting: life table analysis and clinical relevance. J Vasc Surg 38:1162-1168.https://doi.org/10.1016/j.jvs.2003.08.021
  24. Norris JW, Zhu CZ, Bornstein NM, Chambers BR(1991) Vascular risks of asymptomatic carotid stenosis. Stroke 22:1485-1490.https://doi.org/10.1161/01.STR.22.12.1485
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