Role of Biomarker in the Diagnosis of Neurodegenerative Diseases

Abstract

Objectives: Biomarker or biological makers are a molecule that behaves as indicators of biological states; ideally they should have high sensitivity, specificity, and accuracy in reflecting the total disease burden. Neurodegenerative diseases are a heterogeneous group of disorders characterized by progressive loss of structure and function of the central nervous system or peripheral nervous system.

Conclusion: Neurological biomarkers are present optimum amount in cerebro spinal fluid (CSF), but they are also present in blood at low levels. In this review we discuss the current status of the biomarkers used in the neurological disorders.