Hyperinsulinemia: Diagnostic and Treatment Considerations

Abstract

Hyperinsulinemia may be the first indicator of developing metabolic disease and has been linked to insulin resistance, obesity, prediabetes, and type 2 diabetes. Diagnosis of hyperinsulinemia is complex, as signs and symptoms may not be present until other metabolic abnormalities have developed. Formal testing guidelines and a standardized approach to testing for hyperinsulinemia are needed. Practitioners can recommend and emphasize the importance of lifestyle modifications to prevent hyperinsulinemia and subsequent metabolic disease.