Cancer and Culture: Revolutionizing Breast and Cervical Cancer Strategies for Asian Women Using Artificial Intelligence View PDF

The heterogeneity in cancer screening behaviors and risk factors among Asian American subgroups highlights the need for targeted, culturally relevant interventions. Factors such as acculturation, education, health insurance, and access to care significantly influence screening rates [1-3]. Community-based programs using lay health workers, culturally tailored materials, and navigation assistance have shown promise in increasing screening rates and addressing disparities [4]. Furthermore, the effectiveness of polygenic risk scores developed for European-ancestry women in predicting breast cancer risk among Asian women suggests potential for risk-stratified screening programs in Asia [5].

Breast cancer incidence rates have been rising steadily in many Asian countries over the past few decades [6]. This trend is largely attributed to the rapid urbanization and widespread adoption of Western lifestyles, which often include changes in diet, physical activity levels, and reproductive patterns. The shift towards a more sedentary lifestyle, coupled with increased consumption of processed foods and alcohol, has contributed to higher obesity rates and hormonal imbalances, both of which are known risk factors for breast cancer [7, 8]. However, it is crucial to note that Asian women tend to develop breast cancer at a younger age compared to their Western counterparts. This earlier onset poses significant challenges for screening programs and early detection efforts. Additionally, Asian women are more likely to present with more aggressive subtypes of breast cancer, such as triple-negative breast cancer, which is associated with poorer prognosis and limited treatment options. These factors underscore the need for tailored screening guidelines and treatment protocols that account for the unique characteristics of breast cancer in Asian populations [9, 10].

Cervical cancer remains a significant health burden in many Asian nations, despite being largely preventable through human papillomavirus (HPV) vaccination and regular screening programs [11, 12]. The high incidence and mortality rates associated with cervical cancer in Asian countries are particularly concerning, given that effective prevention and early detection methods are available [13]. However, several factors contribute to the persistence of this preventable disease in Asian populations. One of the primary challenges in addressing cervical cancer in Asian women is limited healthcare access, particularly in rural and underserved areas [14, 15]. Many women lack access to regular gynecological care, HPV vaccination, and cervical cancer screening services. This lack of access is often compounded by financial barriers, as many women may not have the means to afford preventive care or cancer treatment [16, 17]. Cultural barriers also play a significant role in the high cervical cancer burden among Asian women.

In many Asian cultures, there is a stigma associated with discussing reproductive health issues, which can lead to reluctance in seeking medical care or participating in screening programs [18]. Additionally, traditional beliefs and practices may sometimes conflict with modern medical approaches, further complicating efforts to implement effective prevention and treatment strategies [19, 20]. Lack of awareness about cervical cancer, its causes, and prevention methods is another critical factor contributing to the high disease burden [21]. Many women may not understand the importance of regular screening or the link between HPV and cervical cancer. This knowledge gap can result in delayed diagnosis and poorer outcomes, as women may not recognize early symptoms or seek medical attention until the disease has progressed to more advanced stages.