Changes in the intestinal microbiota have been associated with inflamatory diseases, leaky-gut, obesity, Cardio-metabolic diseases, breast câncer, polycystic ovary syndrome and stress-related disorders, mainly depression, anxiety, attention deficit and irritable bowel syndrome. From the balance of the microbiome, it is possible to achieve an immunological and metabolic balance and, consequently, there will be, in a practical way, the control of microbial proliferation, mainly of pathogenic bacteria. Intestinal modulation can stimulate the immune system, regulate the absorption and digestion of nutrients, produce compounds necessary for tissue renewal, in addition to minimizing metabolic, autoimmune and behavioral diseases.
Intestinal Dysbiosis, Cardio-metabolic Diseases, Breast Cancer
Intestinal Microbiome and Intestinal Dysbiosis
The intestinal microbiome is defined as the collective genomes of microorganisms that inhabit the intestinal tract . The intestinal microbiota can cause changes that may be related to the brain, thyroid, lung, stomach, intestine, kidneys, liver, heart, skin, adipose tissue, metabolic changes or even autoimmune diseases .
Bacteroidetes, Firmicutes, Actinobacteria and, to a lesser extent, Proteobacteria, are part of the human microbiota, and in other organs, in order to maintain the proper functioning of the intestinal microbiota, a balance between the species of bacteria that compose it is necessary. Large changes in the proportion between these phyla or the expansion of new bacterial groups lead to a disease-promoting imbalance, also known as dysbiosis . A reduction in the diversity and bacterial growth of Proteobacteria are characteristic of dysbiosis. Dysbiosis can be a trigger for inflammatory diseases, for low-grade intestinal inflammation or even for the so-called Leaky Gut.