Overview of Women Related Cancers View PDF

*Ariel Pablo Lopez
Department Of Genetics, Molecular Biology Laboratory, Universidad De Buenos Aires, Argentina

*Corresponding Author:
Ariel Pablo Lopez
Department Of Genetics, Molecular Biology Laboratory, Universidad De Buenos Aires, Argentina
Email:aplopez@prensamedica.com.ar

Published on: 2020-01-27

Abstract

In India, around 5.8 lakhs new cases of cancer are diagnosed in women in 2018. The incidence of breast cancer accounts for 25-32% of all female cancers. 90% of women diagnosed with breast cancer do not have a family history of cancers. Cervix cancer is the second most cancer and accounted 16.5% of newly diagnosed cancer cases in women in the year 2018. Ovarian Cancer is the third leading cancer and accounted for about 6.2% of all cancers among women in our country. India has more than 50% of all the cancers diagnosed in women. They are mostly found in breasts (27.7%), cervix uteri (16.5%), ovary (6.2%) and colorectum (3.4%).

Keywords

Women; Cancer; Cervical Cancer; Breast Cancer

Introduction

Women have emerged winners in balancing home and work. But in the zeal to be the best mother, sister, daughter, wife, friend, colleague, she often lets her well-being and health take a back seat and sometimes it costs her and her dear ones dearly [1,2].

The negligence and ignorance are causing a growing number of women to lose the battle to cancer. Early detection can help more women win the battle against cancer. The biggest challenge is education and awareness about check-ups [3,4].

There is a rising incidence of cancers in India. Breast, cervix, ovarian, uterine and colorectal cancer together account for more than 50% of cancers in women. Many of these cancers can be detected early and are highly curable in early stages. Therefore, it is important to step up and educate our community about cancers in women. Cancer awareness and early detection programs will save lives [5].

Common Cancers in Women

Breast Cancer

Facts

  • In India, Breast cancer is the most common cancer in women.
  • It accounts for a quarter of all cancers diagnosed in a woman.
  • Data shows that women in India are diagnosed at a younger age compared to west.
  • 90% of women diagnosed with breast cancer do not have a family history of cancers.

Possible symptoms

Lump or thickened area of the breast, discharge from either of the nipples, change to the size or shape of breast or nipple, skin irritation or dimpling on the skin of the breast, nipple retraction, breast or nipple pain, breast skin appears red and scaly [6].

Risk factors

Being obese/overweight, hereditary/family history of breast cancer, dense breasts, alcohol consumption, more years of menstruation, never been pregnant.

Cervical Cancer

Facts

  • Cervical cancer is the second most cancer in India in women.
  • Cervix cancer accounted 16.5% of newly diagnosed cancer cases in women in the year 2018.
  • It can be detected early by Pap smear examinations.
  • Early stage Cervix cancer is curable.
  • Cervical Cancer vaccines are very effective in the prevention of cervix cancer.

Possible symptoms

Abnormal vaginal bleeding, pain and discomfort during sex, unusual or unpleasant vaginal discharge, pain in the lower back or pelvis, painful urination.

Risk factors

Early onset of sexual activity (before age of 21), multiple sexual partners, high risk sexual partner human papillomavirus (HPV) infection, immune system deficiency, genital Herpes, smoking and low socio-economic factors.

Ovarian Cancer

Facts

  • It is the third leading cancer in women in India [7].
  • Ovarian Cancer accounted for about 6.2% of all cancers among women in our country.
  • Patients usually present with vague symptoms and this cancer is usually detected at a late stage.

Possible symptoms

Abnormal vaginal bleeding, abdominal bloating, indigestion or nausea, pain and pressure in lower back or pelvis, frequent urination, change in bowel movements, changes in menstruation, loss of appetite, weight and fatigue.

Risk factors

Older age, genetic factors, being overweight or obese, endometriosis.

Uterine Cancer

Facts     

  • The incidence of uterine cancers in India is very low.
  • Post-menopausal bleeding is the most common symptom of uterine cancer and should not be ignored.
  • Early stage uterine cancer is highly curable.

Possible symptoms

Abnormal, heavy or irregular menstruation, pain and discomfort during intercourse, unusual or unpleasant vaginal discharge (foul smelling, pus-like or blood tinged), pelvic pain or pressure, painful urination, loss of appetite, weight loss, painful bowel movements, bleeding from bladder or rectum [8,9].

Risk factors

Changes or imbalance in the female hormones, Increasing Age, being obese, genetics, family history (having endometrial or colorectal cancer), breast cancer treated with Tamoxifen, increased exposure to estrogen hormone, never been pregnant, more years of menstruation.

Colorectal Cancer

Facts

  • Colorectal cancer accounts for about 3.9% of all cancers in women in India [10].
  • The incidence of colorectal cancer in India is rising.

Possible symptoms

Persistent change in bowel habits (narrow stools, constipation, diarrhoea, excessive bloating or gas), rectal bleeding or blood in stools, persistent abdominal discomfort, weakness or fatigue, unintended weight loss, cramping or abdominal pain.

Risk factors

Increasing age, personal history of colorectal cancer or polyps, inflammatory intestinal conditions, inherited syndromes that causes increased risk of colon cancer, family history of colon cancer, low-fibre and high-fat diet, sedentary lifestyle, diabetes, obesity, smoking, alcohol consumption [11].

References

  1. United News of India (2020) 5.8 lakh new cancer cases diagnosed in women in India in 2018: AOI.
  2. Chaturvedi AK (2010) Beyond cervical cancer: burden of other HPV-related cancers among men and women. J Adolesc Health 46:S20-S26.https://doi.org/10.1016/j.jadohealth.2010.01.016
  3. Avis NE, Crawford S, Manuel J (2005) Quality of life among younger women with breast cancer. J Clin Oncol 23:3322-3330.https://doi.org/10.1200/jco.2005.05.130
  4. Agarwal G, Ramakant P (2008) Breast cancer care in India: the current scenario and the challenges for the future. Breast Care 3:21-27.http://dx.doi.org/10.1159/000115288
  5. Malvia S, Bagadi SA, Dubey US, Saxena S (2017) Epidemiology of breast cancer in Indian women. Asia Pac J Clin Oncol 13:289-295.https://doi.org/10.1111/ajco.12661
  6. Sreedevi A, Javed R, Dinesh A (2015) Epidemiology of cervicalcancer with special focus on India. Int J Womens Health7:405.https://dx.doi.org/10.2147/IJWH.S50001
  7. Staff A (2018) Cancer facts and figures 2018. American Cancer Society, United States.
  8. Ahlberg K, Ekman T, Gaston-Johansson F (2005) The experience of fatigue, other symptoms and global quality of life during radiotherapy for uterine cancer. Int J Nurs Stud 42: 377-386.https://doi.org/10.1016/j.ijnurstu.2004.07.008
  9. Rajaram S, Chitrathara K, Maheshwari A, editors. Uterine cancer: diagnosis and treatment. Springer; 2015 Aug 27.
  10. Potter JD (1996) Nutrition and colorectal cancer. Cancer Causes Control 7: 127-146.https://doi.org/10.1007/BF00115644
  11. Indian Council of Medical Research (2014) The Consensus Document on Management of Cancer.
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