Modified Platelet Rich Plasma (PRP) Technique in Repair of Primary Cleft Palate

Ibrahim ELdsoky,

Published on: 2020-01-21


Objectives: To evaluate the effect of Platelet rich plasma (PRP) applied during primary repair of complete cleft palate and comparing the results with those obtained without PRP application.
Design: A prospective randomized study.
Setting: All patients attending at pediatric surgery and otolaryngology departments, Al-Azhar University hospitals, Cairo, Egypt.
Patients: Forty patients divided into two equal groups. All patients underwent 2- flap technique palatoplasty. Group A; 20 patients had PRP injection (3-5ml injected in each layer) during palatoplasty, while group B; 20 patients without PRP application. All patients were followed up in the out-patient clinic for 13 (12-17) months.
Results: Forty patients presented with complete cleft palate, 25 males and 15 females, with a mean age of 18 months (12-24 months). All patients undergone 2-flap palatoplasty with no intra-operative complications. In group A, no cases of postoperative fistula (0%) after palatal surgery, while fistula occurred in 4 cases (20%) of patients in group B. The fistula occurrence in group A was lower than that in group B (p=0.08) with no statistically significant difference.
Conclusions: PRP application is feasible and effective technique. Fistula formation after primary palatoplasty is decreased with PRP application.

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