Multiple Myeloma: A Review in Single Center Experience

Abstract

Background: Multiple myeloma (MM) is a clonal plasma cell neoplasm associated with monoclonal para proteinemia, bone marrow plasmacytosis, bone lesion, hypercalcemia, and anemia. Chemo-immune regimens are commonly used for treatment of multiple myeloma. The present study aimed at determining the characteristics and outcomes of patients with multiple myeloma treated at our center.
Methods: During March 2016 and December 2019, all patients with confirm diagnosis of MM were included in this study. Data were collected from hospital information system. The characteristics and outcomes of all patients were analyzed.
Results: A retrospective review of 75 patients. Median age was 65 years, with 50% ≤ 65 years. Most of the patients (n=42; 56%) were male and 33 (44%) were female. More than two-third (88% (presented musculoskeletal symptom: bone pain (88%), anaemia 50%. Myeloma-related organ impairment included hypercalcaemia (16%), renal impairment (8%), 84% of patients were diagnosed in advanced stage (II/III) according to durie Salmon classification.
Conclusion: Based on our results, the onset of multiple myeloma occurs in relatively younger age groups but with more advanced stage