Risk Factors Associated with Mortality in Patients with Covid-19

Abstract

Introduction: The appearance of a new coronavirus, SARS-CoV-2, has been classified in 2019 as a pandemic by the WHO, having to date more than 170 million infected and 3.53 million deaths.

Objective: This article aims to conduct a systematic review of several scientific publications about the risk factors associated with mortality in patients with COVID-19. Methods: The review was conducted through an electronic search of several scientific articles related to this topic. The PEO question was used: What are the risk factors associated with mortality in patients with COVID-19? The search sources were PubMed, Scielo, and Google Scholar. The keywords used to search were: “coronavirus infections”, in combination with “risk factors” and “mortality”; "infecciones por coronavirus" along with "COVID-19", "factores de riesgo" and "mortalidad". Articles published from May 7, 2020 to April 28, 2021 were selected.

Results: Of the 76 articles found, 57 were discarded for not meeting our inclusion and exclusion criteria, leaving 19 articles for this review. Significant risk factors for mortality from COVID-19 were: Age > 60 years, male sex, prolonged hospital stay, presence of comorbidities, presence of signs and symptoms of the disease and altered biomarkers, etc.

Conclusion: Various risk factors are associated with mortality from COVID-19: Age> 60 years, male gender, prolonged hospital stay, presence of comorbidities, presence of signs and symptoms of the disease and altered biomarkers, among others.