The Correlation of Vitamin D3 Level and Lund Mackay Score in Patients with Chronic Rhinosinusitis

Abstract

Background: Recently many studies have been highlighted the potential impact of impaired VD3 status in the body as it is a major fighter of inflammation, with a critical role in prevention and treatment of asthma, and a major role in chronic rhinosinusitis. In this study we evaluate relation between vitamin D3 level & LundMackay score system in patients with chronic rhinosinusitis.
Patients & Methods: 34 patients (24 males and 10 females) with chronic rhinosinusitis were enrolled in the study. All patients did a CT scan of nose and paranasal sinuses with assessment of their serum vitamin D3 level.
Results: Vitamin D3 level is seem to be independent on age of the patients & significant negative correlation between Lund-Mackay score & serum vitamin D3 level, no significant correlation was found between Lund-Mackay score & age & gender of the patients.
Conclusion: There is an inverse relationship between level 25 hydroxyvitamin D3 and severity of mucosal disease in chronic rhinosinusitis patients.