The Relation of HbA1c and Vitamin D with some Biochemical Variables in the Blood of Type1 Diabetic Patients in Tikrit

Abstract

Diabetes is a group of metabolic diseases characterized by a high level of sugar in the blood as a result of a defect in insulin secretion or insulin function or both, it is a common disease in the world. The study aimed to measure the biochemical variables in type 1 diabetes patients, as it included (Urea, AST, ALT, ALP, Creatinine, and Bilirubin) which are biochemical variables to know the efficiency of the liver and find a relationship between those variables HbA1c and Vitamin D.
The results showed a noticeable increase in the levels of glucose and the percentage of HbA1c, which is a natural increase in the blood in diabetics compared with healthy people, and the results also showed high standard variables for liver efficiencies such as urea, creatinine, and liver function enzyme (AST, ALT, ALP) in diabetics compared with healthy people. In addition to a significant decrease, the probability level of 0.05 vitamin D in patients compared with healthy subjects.
It was found through the results of correlations and finding the correlation coefficient between glycated hemoglobin and the measured variables that HbA1c correlates positively with ALP, AST and urea enzymes while correlation negatively with creatinine, bilirubin and vitamin D in addition to ALT in patients with type 1 diabetes and with variable correlation coefficient values, while vitamin D correlated was negative with different correlation coefficients in patients with all variables, while AST had a positive correlation with a small percentage with a correlation coefficient of 0.031.