Treatment of Condyloma Acuminata in the Penis with Subcutaneus Interferon Alfa 2b: Report of a Case

Abstract

Condyloma acuminata, also known as genital warts, are lesions caused by the human papillomavirus (HPV). Genotypes 6 and 11 are responsible for more than 90% of cases. They represent one of the most common sexually transmitted diseases. The usual locations are external genitalia (penis, vulva, perineum, and perianal skin), cervix, vagina, urethra, and anus. Diagnosis is generally clinical. Factors to consider in selecting treatment include the size, number, and morphology of the lesions, the affected anatomical site, patient preference, cost, convenience, side effects, and the professional’s experience. Many patients require more than one treatment. Interferon (IFN) is a group of glycoproteins that are naturally produced and have antiviral, antiproliferative, and immunomodulatory properties. When administered subcutaneously, it is an effective, non-invasive therapeutic option with few side effects for multiple condyloma acuminata. We present a patient with multiple condyloma acuminata with a very satisfactory response to subcutaneous IFN alpha 2b.