Calculation of Stopping Power for protons in Biological Human parts View PDF

*Saddam AH Abd Ali
Department Of Physics, Faculty Of Education For Girls, University Of Kufa, Iraq

*Corresponding Author:
Saddam AH Abd Ali
Department Of Physics, Faculty Of Education For Girls, University Of Kufa, Iraq
Email:alwailysaddam@gmail.com

Published on: 2020-04-17

Abstract

In this research, a theoretical study was carried to calculate the mass stopping power by using Ziegler equations and fitting equations for protons in biological Human parts (Water, Bone, Muscle, Tissue, Trachea, and Adipose tissue) in the range of energy (1-100000) KeV. The data extracted from SRIM 2013 program was used to protons to the same mediums applied in the Matlab program. The correlation coefficient (r) was calculated between the data Ziegler equation and the SRIM 2013 program data. A fairly good agreement has been found between our simplified values for mass stopping power of protons for Water, Bone, Muscle, Tissue, Trachea, and Adipose tissue.

Keywords

Ziegler, Stopping power, Human tissue

Introduction

The loss of energy for particles in the matter studied for many years as result for collision phenomena, where the charged particle loss its kinetic energy in different ways of reaction dependent on the velocity and nuclear charge for incident charged particle and also on the nature of target particles [1].

A charged particle moving rapidly through matter loses energy primarily by ionizing and exciting atoms. An important goal of theoretical understanding of these processes is the prediction of the average rate of energy loss of the particle per unit distance traveled as a function of the particle’s energy. This fundamental quantity is called the stopping power of the material for that particle [2].

The electronic stopping term governs the energy losses caused by the electronic interactions, which can be further divided into several different contributions depending on the nature of the interaction. Hence, the stopping power can be written as [3].

It is often denoted by the symbol dE/dx and expressed in the units MeV/cm. Dividing the stopping power by the density ρ of the material gives the closely related mass stopping power,- dE/ρdx, which can be expressed in [2].

The stopping power depends on the type and energy of the particle and on the properties of the material it passes. Since the production of an ion pair (usually a positive ion and a negative ion (electron) requires a fixed amount of energy, the density of ionization along the path is proportional to the stopping power of the material. Stopping power refers to the property of the material while energy loss per unit path length describes what happens to the particle [4]. The stopping power of light and heavy particles depends mainly and directly on the projectile's charge and speed, and the increase in the particle's energy leads to a decrease in the linear stopping power. This means that it is inversely proportional to the projectile's energy [5].

Theory

In 1913, Niels Bohr derived nuclear formula for the Stopping power of heavy charged particles, based on classical physics. In 1934, Beth developed a formula similar to the Bohr formula to calculate the Stopping power by relying on quantum theory within the limits of high [6]. It has been shown that, depending on the value of the parameter η = / v , where is the atomic number of a bare ion moving with velocity v, the energy losses can be described classically if η>>1, and the quantum perturbation approach is applicable at the opposite limiting case of small η [7]. From the collision principle of Bohr  classic theory and the principle of momentum and transmitted energy to quantum

Beth’s Theory, the final Stopping power for Beth – Bloch is [8].

<I> is the rate of ionization potential of the electrons, Y( Z1) relative stopping function in terms of the atomic number of the falling particle ,which is a small amount containing Bloch  correction. The rule says the mass stopping power for the substance containing several elements is taken to be equal to the weighted sum of the mass stopping power of the constituent atoms [9].

There has never been a detailed calculation of the stopping of low- energy light ions in solids which has been shown to be even modestly accurate for abroad range of targets. This may be because there is no accurate way to calculate the dynamic charge distribution of light ions inside solids [10]. Ziegler was able devise a formula for calculating the ability to Bloch active light ions (H, He, Li) at energies above 1MeV. Experimental proton stopping power data are summarized by Anderson and Ziegler. Reliable data are available for many elements over a wide range of energies [8]. However, in order to obtain values for all elements over a continuous range of proton energies, the authors fit curves through the available experimental data to generate coefficients for use in a semi-empirical parameterization of the stopping power as a function of proton energy E (keV) and the target atomic number Z2. S is assumed to be proportional to E0.45 for E <25 keV, except for Z2 6, where it is proportional to E0.25; for 25 keV E 10000 MeV, Ziegler F, et al. (1977) [11]. 

and the coefficients Ai for each Z2, available from TRIM, For 10 MeV E 2 GeV, TRIM2 includes four additional coefficients A9 through A12, for use in the parameterization [11].

Results And Discussion

Stopping power Was calculated by Ziegler and applied to the elements only in the three equations (4,5, and 6) through our research, for the first time the stopping power was calculated on six different types of parts of the human (Water, Bone, Muscle, Tissue, Trachea, Adipose tissue) and with an energy range (1-100000)KeV. The program has been implemented in a language Matlab 2012.

Ziegler equations

By program SRIM 2013 which was implemented in Matlab program we have used the major Ziegler equation in low and high energies where it is represented as follows:

S1 = SLOWSHIGH  / (SLOW+SHIGH)       (8)

Where: (S1) Represent stopping power total, (SLOW) Low energy Stopping power, (SHIGH) High energy stopping power

Zieglers equation of stopping power are divided into three regions [8].

  • The first region is the low energy region with energy range of (1-10) KeV and is shown in the following formula
  • The second region of the Ziegler equation for the stopping power with energy range of (10-1000) KeV divided into two regions is shown in the following formulas
  1. Low energy equation in the second region as follows
  1. High energy equation in the second region as follows
  1. The third region of the Ziegler equation for the stopping power with energy range of ( 1000 – 100000) KeV is shown in the following formula

From A1 to A8 is constant as shown in table 1 of the water and oxygen.

Table 1: Values of constants for protons.

Element

A1

A2

A3

A4

A5

A6

A7

A8

H

1.262

1.44

242.6

1.2E4

0.1159

0.0005099

5.436E4

-5.052

O

2.652

3

1920

2000

0.0223

0.004079

1.046E4

-6.734

Table 2: Correlation coefficient values when comparing the protons stopping power resulting from Ziegler equation and SRIM2013.

Project

Human Tissue

CORREL

Water

0.9992

Proton

Bone

0.999

Muscle

0.9991

Tissue

0.9991

Trachea

0.9992

Adipose tissue

0.998

Fitting equations

At low energies E < 400 keV, stopping power theory is mostly evaluated using the Thomas-Fermi statistical model of the atom. The energy loss processes are divided up into electronic energy losses and elastic energy losses to the screened nuclei. For hydrogen projectiles, the nuclear stopping power is very small for all energies of interest here. (~1-2% at 10 keV and increasing in relative importance with decreasing energy). Electronic stopping was found to increase in high energies and proportional to the speed projectile, one basic conclusion of Andreson and Ziegler study is that the entire experimental material considered does not give indication of any influence of projectile mass on stopping powers [11]. By program SRIM 2013 which was implemented in MATLAB program, we have used a curved fitting with Ziegler equations we concluded that results are very good as in the figures (Figure 1-Figure 6). Table 1 shows values of constant H and O and Table 2 shows values of constant.

Conclusion

Through the research results that we reached to calculate the total stopping power by using Ziegler equations and with an energy range (1-100000) KeV, it was found that the nuclear stopping power decreases at low energies less than 400KeV and decreases with the decrease in energy, while the electronic stopping power is greater than the nuclear stopping power at these energies and the more they increase energy increases the irritation of the atoms, and consequently, the electronic stopping power increases at high energies greater than 400KeV, where it was found through calculations that they depend on the speed projectile and undepend on the mass projectile. By calculating the Ziegler equations to calculate the total stopping power in the studies tissue, it was found that results of the curve match are close to the practical results.

References

  1. Mohammed AG (2014) Range and Stopping Power Calculation for protons of some compounds. Thesis, University of Kufa, Iraq.
  2. Kadhim RO, Ali NS (2019) Calculation of stopping power and stopping time for protons in human tissues. Prensa Med Argent, Volume 105: 164.
  3. Peltola J (2003) Stopping power for ions and clusters in crystalline solids. Report Series in Physics, University of Helsiniki, Finland.
  4. Getachew A (2007) Stopping power and range of protons of various energies in different materials. Addis Ababa University, Ethiopia.
  5. Csete A (2002) Experimental investigations of the energy loss of slow protons and antiprotons in matter. University of Aarhus, Denmark.
  6. Turner JE (2004) Interaction of ionizing radiation with matter. Health Phys 86: 228-252.
  7. Khodyrev VA (2000) On the origin of the Bloch correction in stopping. J Phys B At Mol Opt 33: 5045-5056.
  8. Ziegler J (1999) Stopping of energetic light ions in elemental matter. J Appl Phys 85: 1249-1272.
  9. Owaid Kadhim R, Mutar ZH (2019) Calculation of stopping power for protons, carbon and oxygen ions in C2H4O, C3H3N polymers. Journal of Kufa-physics 11: 101-105.
  10. Ziegler JF (1977) The stopping and ranges of ions in matter. Elsevier, Netherlands.
  11. Andersen HH, Ziegler JF (1977) Hydrogen stopping power and Range in all elements. Pergamon press, New York.
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