Effect of Paracetamol Intravenous Infusion on Duration and Quality of Spinal Blockade in Patients Undergoing Major Gynaecological Surgeries: A Prospective, Randomised, Double-Blinded, Placebo-Controlled Study View PDF

^*Sandeep Kumar Kar
Department Of Cardiac Anesthesiology, IPGME & R, Kolkata, India

^*Corresponding Author:

Sandeep Kumar Kar
Department Of Cardiac Anesthesiology, IPGME & R, Kolkata, India
Email:sndpkar@yahoo.co.in

Published on: 2014-08-29

Abstract

Effective pain management is an important component of post-surgical care. For pain relief after major gynecological surgeries, particular attention has been paid to NSAIDs and paracetamol. Paracetamol (acetaminophen) is one of the most commonly used antipyretic analgesics for the symptomatic treatment of acute pain and fever. This study was conducted with the primary aim of evaluating the effect of intravenous paracetamol infusion on the onset and duration of sensory-motor blockade in patients undergoing elective major gynecological surgeries under spinal anesthesia.

Keywords

Paracetamol; Tramadol; Spinal anesthesia

Introduction

Pain is an unpleasant emotional and sensory experience associated with active or potential tissue damage. Acute postoperative sequelae, such as pain, nausea, and drowsiness, tend to produce an unfavorable effect on patients’ general well-being and increase perioperative morbidity as well as the length of hospital stay. 40 to 70% of patients report moderate to severe pain after surgery hampering ambulation, discharge and satisfaction.