Links between Leukemia, Obesity and Vitamin-D Deficiency in a Cross Sectional Study in the North of Saudi Arabia View PDF

^*Faris Q Alenzi
Department Of Immunology, College Of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, Saudi Arabia

^*Corresponding Author:

Faris Q Alenzi
Department Of Immunology, College Of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, Saudi Arabia
Email:qalenzi@ksu.edu.sa

Published on: 2016-06-23

Abstract

Vitamin D deficiency has recently been recognized as a worldwide concern and still linked to obesity. Despite its high prevalence, no previous community based studies have been conducted in Arar; northern border of Kingdom of Saudi Arabia (KSA), addressing this issue could be traced. This study was carried out to show the magnitude of the problem of vitamin D deficiency and how such a deficiency can eventually has associated with overweight and obesity in female Arar population, KSA.

Keywords

Vitamin D deficiency; Overweight; Obesity; Females; Kingdom of Saudi Arabia

Introduction

Apparently, obesity is associated with a low-grade inflammation of white adipose tissue (WAT) resulting from chronic activation of the innate immune system. Excess fat is thought to stimulate white blood cells (WBCs) that produce inflammatory molecules as a part of the normal immune response upon injury or infection. Obese adipose tissue mainly releases pro-inflammatory cytokines including: TNF-α, IL-6 and leptin. At biology level, it can be influenced by a variety of complement components.