Natriuretic Peptide Levels and Early Respiratory Adverse Outcome in Cardiac Surgery: A Short Review of the Literature View PDF

Konstantinos Giakoumidakis
Department Of Cardiovascular Surgery, Evangelismos Hospital, Athens, Greece

Published on: 2014-12-10

Abstract

B-type natriuretic peptide and N-terminal pro-Btype natriuretic peptide are significant biomarkers for predicting outcome among cardiac surgery patients. Their elevated levels have been strongly associated with increased mortality, prolonged intensive care unit stay and postoperative onset of atrial fibrillation. However, early respiratory morbidity indexes have not been long studied.

Keywords

B-type natriuretic peptide; Cardiac surgery; Natriuretic peptide; Nterminal pro-B-type natriuretic peptide; Outcome; Respiratory complications

Introduction

B-type natriuretic peptide (BNP) and N-terminal pro-B-type natriuretic peptide (NT pro-BNP) are synthesized and released by ventricular cardiomyocytes in response to ventricular dysfunction and increased wall-stress.