Oro-Periodontal Manifestations of Langerhans Cell Histiocytosis (Eosinophilic Granuloma) View PDF

^*Hassan Yehya Mohammed Alqudaimi
Department Of Dentistry, Ibb University, Yemen

^*Corresponding Author:

Hassan Yehya Mohammed Alqudaimi
Department Of Dentistry, Ibb University, Yemen
Email:kaisa.raninen@uef.fi

Published on: 2016-03-28

Abstract

A 25-years-old man suffering from tooth mobility and dental loss was seen at the Clinic of the Department of oral medicine and Periodontology, faculty of dentistry, Mansoura university, Egypt. Investigated revealed clinical and radiographic with radiolucent images massive diffuse alveolar bones around of both molar and premolar areas in the mandible, mirror-like image and the posterior teeth gave an image of "floating teeth.

Keywords

Periodontal disease; Eosinophilic granuloma; Langerhans cell histiocytosis

Introduction

Langerhans cell histiocytosis (LCH), which was previously termed “histiocytosis X,” is a rare clonal disorder characterized by the proliferation of clonal CD1a-positive immature dendritic cells (LCH cells) in the skin, bone, lymph nodes and other organs. The clinical manifestations of LCH vary from a self- limiting single bone disease to rapidly fatal disseminated disease. However, LCH usually follows a chronic course and reactivations often occur. This can result in permanent consequences, such as orthopedic abnormalities, the development of central diabetes insipidus (CDI), and neurodegenerative central nervous system (ND-CNS) disease