Potential Leukocytic Toxicity Induce by Vinorelbine, Doxorubicin and Cisplatin in Human Patients of Breast, Cervix and Lung Cancer View PDF

^*Taha Nazir
Department Of Biochemistry, University Of Sargodha, Pakistan

^*Corresponding Author:

Taha Nazir
Department Of Biochemistry, University Of Sargodha, Pakistan
Email:tahanazir@yahoo.com

Published on: 2015-07-25

Abstract

Anticancer drugs are used extensively in chemotherapy. Bone marrow suppression is one of their major side effects. Therefore, we aimed this study to investigate the potential leukocytic toxicity induced by vinorelbine in cancer patients. The data of total 60 adult patients were selected and divided into two groups; Group-1 patients received Vinorelbine alone and group-2 Vinorelbine based combinations. The outcomes demonstrated no statistically important difference in the patients who were either on vinorelbine alone, vinorelbine plus cisplatin or vinorelbine plus doxorubicin combinations.

Keywords

Leukocytonia; Leucopenia; Vinorelbine; Cisplatin; Doxorubicin; Breast cancer; NSCLC

Introduction

Cancer is a fatal dilemma of human life and more mysterious of the major life threatening diseases. Despite of the scientific miracles, cancer is still a very real concern to public health, both in perception and reality. It is being treated stereoscopically with good or bad results by using surgical, radiological or chemotherapeutic methods.