Acrokeratosis Verruciformis of Hopf: Report of a Case of Onset in Adulthood and Review of Literature
Pablo Zini, Juliana Martínez Del Sel, Dante Chinchilla, Myriam Dahbar, Jesica Rios, Graciela Manzur,
Published on: 2026-04-03
Abstract
Acrokeratosis verruciformis (AKV) of Hopf is a rare genodermatosis of autosomal dominant inheritance that is characterized by the presence of keratotic papules of symmetrical arrangement in rubbing areas on the back of the hands and/or feet. There are few cases of sporadic presentation in adulthood. The histopathological study shows the typical “church capitals”. Due to its benign evolution, treatment is indicated at the request of patients for aesthetic reasons. We present a 76-year-old patient with sporadic Hopf’s verruciform acrokeratosis of onset in adulthood.
