Character of Changes of the Absolute and Relative Amounts of the Main Populations of Immune-Competent Cells of the Peripheral Blood of Children with Visual Impairments

Dychko V,

Published on: 2020-09-21


The purpose of the study was to investigate the nature of changes of the absolute and relative numbers of major populations of immune-competent cells of peripheral blood of children with visual impairment aged 7-10 years.
We surveyed 63 children at the age of 7-10 years, including children with visual impairments (14 boys and 17 girls) average age of whom is 8.48 ± 0.13 years, and practice healthy peers with normal vision (16 boys and 16 girls) an average age of whom is 8.53 ± 0.13 years.
Whole blood was selected to study the level of adaptive stress, cellular reactivity of the body of children with visual impairments. Blood for general analysis was taken not from the finger, so as not to disturb the sensory mechanisms (sense of touch) of sensitivity of children with disabilities, but from the elbow vein. Blood tests were carried out by well-known and accepted methods worldwide.
It is established that in children with visual disorders the tendencies of increasing of absolute and relative number of ICCs are formed, involved in realization of nonspecific anti-infective protection, as well as increasing of absolute number of lymphocytes and decreasing of relative number of lymphocytes and monocytes. Also, it is established that absolute number of leukocytes in the peripheral blood of girls is dominated by the absolute number of leukocytes in boys with vision impairment - by 9.12% (P <0.05), the relative number of eosinophils - by 39.86% and ESR - by 13.34%.

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