Effect of Paracetamol Intravenous Infusion on Duration and Quality of Spinal Blockade in Patients Undergoing Major Gynaecological Surgeries: A Prospective, Randomised, Double-Blinded, Placebo-Controlled Study

Abstract

Effective pain management is an important component of post-surgical care. For pain relief after major gynecological surgeries, particular attention has been paid to NSAIDs and paracetamol. Paracetamol (acetaminophen) is one of the most commonly used antipyretic analgesics for the symptomatic treatment of acute pain and fever. This study was conducted with the primary aim of evaluating the effect of intravenous paracetamol infusion on the onset and duration of sensory-motor blockade in patients undergoing elective major gynecological surgeries under spinal anesthesia.