Familial Y Micro deletion with Cleft Lip

Abstract

Cleft lip and cleft palate are frequent congenital malformations that occur as isolated presentations or as a constellation of symptoms with other genetic complications or as part of a specific genetic syndrome. However, there have only been few reports of cleft lip or palate with Y chromosome abnormalities. We report a rare case of familial Yq11.22-Yq11.23 micro deletion with cleft lip and palate.